This is the methods home page of the Macromolecular Crystallography Core Facility in the Dept. of Molecular Biology at Princeton University. This page was created by and is managed by the Crystallography Facility Manager - Phil Jeffrey - to assist in the nuts and bolts of working on crystal structures. In contrast to the Molbio Crystallography Core Facility Home Page this page is not an official Molbio or Princeton product. It contains a lot of utilitarian data intended for use by crystallographers during structure determination. The content here is provided in the hope that some of it will be useful. Copyright is maintained by the original authors - there are many links to outside sources of information within these pages. Comments to the Facility Manager: Phil Jeffrey, 8-3978, Schultz 219 or preferably via EMAIL.

As of 2014 we now run a crystallography core facility dedicated to providing services for crystallization, x-ray data collection and data analysis. Our equipment includes a Rigaku RuH3R rotating anode generator and RAXIS IV++ detector, and an Art Robbins Phoenix crystallization robot. Our services also include consultation on difficult structures - hopefully with the current software tools and perhaps even the pages/links below you can determine straightforward structures yourself, but of the 100+ structures I've solved over the years quite a few have been less than simple.

Caveat: there is still a lot of inconsistency about the look-and-feel of these pages. It's a choice between adding content or spending a month hacking HTML and CSS. The content tends to win because I'm not at heart a graphic designer. I am, however, working on it. Slowly.

 

What's New?

 

Safety

 

Hardware-related Issues

 

Synchrotron Issues

 

Software-related Issues

 

Crystallography/Lab Methods, Tuturials and Guides

Look further down the page for software and servers.

Broken links ? Search for it's new location via Google, then let me know the new URL....

 

Macromolecular Software Home Pages

This list curated August 2010.

 

Bioinformatics Software and Database Search Sites

 

Structural Genomics

Greg Petsko's "An idea whose time has gone" is a rather interesting alternative viewpoint on this subject.

Programming Tutorials (C-shell, C, Fortran etc)

Or search Google for more.

Manufacturers/Vendors

Some of them we use, some of them we do not. Inclusion in this list doesn't mean that we recommend them, just that we are aware of them. There's a fair amount of overlap: mutliple vendors offer Mitegen mounts and Spearlab foam dewars, for example.

  Facility Manager: Phil Jeffrey, Schultz 219, 8-3978, pjeffrey@princeton.edu